The last 16 teams have learnt what lies between them and the UEFA Champions League quarter-finals.
There are nine former winners among the teams through to the UEFA Champions League round of 16. UEFA.com profiles all these high-flying contenders.
Two seeding pots were formed: one consisting of the eight group winners (seeded teams) and the other of the eight runners-up (unseeded teams). No team could be drawn against a club from their group or any side from their association.
Seeded group winners were drawn away in the round of 16 first legs and at home in the return matches.
Benfica (POR) vs Real Madrid (ESP)
Villarreal (ESP) vs Manchester City (ENG)
Atlético (ESP) vs Bayern (GER)
Salzburg (AUT) vs Liverpool (ENG)
Inter (ITA) vs Ajax (NED)
Sporting CP (POR) vs Juventus (ITA)
Chelsea (ENG) vs LOSC Lille (FRA)
Paris Saint-Germain (FRA) vs Manchester United (ENG)
The first legs will take place on 15/16 and 22/23 February, with the returns scheduled for 8/9 and 15/16 March. The draw for the quarter-finals and semi-finals will be held on Friday 18 March.
Saint Petersburg’s Gazprom Arena, home to Zenit, will stage the final of the 2021/22 UEFA Champions League, with the game scheduled for 28 May 2022.
It will be Russia’s second final; Manchester United overcame Chelsea on penalties in the 2008 decider in Moscow.
Recall that the away goals rule has been abolished. If the tie is level after 180 minutes, it goes to extra time. If the teams still can’t be separated after an additional 30 minutes, the tie goes to a penalty shoot-out.
Each club can register a maximum of three new players for the remaining matches by midnight CET on 2 February 2021. Players are allowed to have played for another club in the UEFA Champions League or UEFA Europa League but there are restrictions on the number of ‘List A’ players.